PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons

The fidelity of RNA splicing is maintained by a network of factors, but the molecular mechanisms that govern this process have yet to be fully elucidated. We previously found that TDP-43, an RNA-binding protein implicated in neurodegenerative disease, utilizes UG microsatellites to repress nonconser...

Full description

Bibliographic Details
Main Authors: Jonathan P. Ling, Resham Chhabra, Jonathan D. Merran, Paul M. Schaughency, Sarah J. Wheelan, Jeffry L. Corden, Philip C. Wong
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716311676