The Effect of Neurotoxin MPTP and Neuroprotector Isatin on the Profile of Ubiquitinated Brain Mitochondrial Proteins

The Effect of Neurotoxin MPTP and Neuroprotector Isatin on the Profile of Ubiquitinated Brain Mitochondrial Proteins

Mitochondria are a crucial target for the actions of neurotoxins, causing symptoms of Parkinson’s disease in various experimental animal models, and also neuroprotectors. There is evidence that mitochondrial dysfunction induced by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine...

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Bibliographic Details
Main Authors: Olga Buneeva, Arthur Kopylov, Inga Kapitsa, Elena Ivanova, Victor Zgoda, Alexei Medvedev
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Cells
Subjects:
ubiquitin
proteasome
mouse brain mitochondrial proteins
proteomic profiling of ubiquitinated proteins
MPTP-induced Parkinsonism
neuroprotector isatin
Online Access:http://www.mdpi.com/2073-4409/7/8/91

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http://www.mdpi.com/2073-4409/7/8/91

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