An In Vitro Model for Assessing Corneal Keratocyte Spreading and Migration on Aligned Fibrillar Collagen

An In Vitro Model for Assessing Corneal Keratocyte Spreading and Migration on Aligned Fibrillar Collagen

Background: Corneal stromal cells (keratocytes) are responsible for developing and maintaining normal corneal structure and transparency, and for repairing the tissue after injury. Corneal keratocytes reside between highly aligned collagen lamellae in vivo. In addition to growth factors and other so...

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Bibliographic Details
Main Authors: Pouriska B. Kivanany, Kyle C. Grose, Nihan Yonet-Tanyeri, Sujal Manohar, Yukta Sunkara, Kevin H. Lam, David W. Schmidtke, Victor D. Varner, W. Matthew Petroll
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Journal of Functional Biomaterials
Subjects:
corneal stroma
corneal keratocytes
wound healing
collagen fibrils
growth factors
extracellular matrix
topography
microfluidics
engineered substrates
Online Access:http://www.mdpi.com/2079-4983/9/4/54

Internet

http://www.mdpi.com/2079-4983/9/4/54

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