Genomic analysis of human brain metastases treated with stereotactic radiosurgery reveals unique signature based on treatment failure

Genomic analysis of human brain metastases treated with stereotactic radiosurgery reveals unique signature based on treatment failure

Summary: Stereotactic radiosurgery (SRS) has been shown to be efficacious for the treatment of limited brain metastasis (BM); however, the effects of SRS on human brain metastases have yet to be studied. We performed genomic analysis on resected brain metastases from patients whose resected lesion w...

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Bibliographic Details
Main Authors: Jack M. Shireman, Quinn White, Zijian Ni, Chitrasen Mohanty, Yujia Cai, Lei Zhao, Namita Agrawal, Nikita Gonugunta, Xiaohu Wang, Liam Mccarthy, Varshitha Kasulabada, Akshita Pattnaik, Atique U. Ahmed, James Miller, Charles Kulwin, Aaron Cohen-Gadol, Troy Payner, Chih-Ta Lin, Jesse J. Savage, Brandon Lane, Kevin Shiue, Aaron Kamer, Mitesh Shah, Gopal Iyer, Gordon Watson, Christina Kendziorski, Mahua Dey
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Genomics
Genomic analysis
Cancer systems biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422400823X

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http://www.sciencedirect.com/science/article/pii/S258900422400823X

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