PD-L1 Over-Expression Varies in Different Subtypes of Lung Cancer: Will This Affect Future Therapies?

PD-L1 Over-Expression Varies in Different Subtypes of Lung Cancer: Will This Affect Future Therapies?

Programmed death-ligand (PD-L) 1 and 2 are ligands of programmed cell death 1 (PD-1) receptor. They are members of the B7/CD28 ligand-receptor family and the most investigated inhibitory immune checkpoints at present. PD-L1 is the main effector in PD-1-reliant immunosuppression, as the PD-1/PD-L pat...

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Bibliographic Details
Main Authors: Asad Ullah, Steven Pulliam, Nabin Raj Karki, Jaffar Khan, Sana Jogezai, Sandresh Sultan, Lal Muhammad, Marjan Khan, Nimra Jamil, Abdul Waheed, Sami Belakhlef, Intisar Ghleilib, Eric Vail, Saleh Heneidi, Nagla Abdel Karim
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Clinics and Practice
Subjects:
programmed death-ligand
immunosuppression
autoimmunity
adenocarcinoma
Online Access:https://www.mdpi.com/2039-7283/12/5/68

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https://www.mdpi.com/2039-7283/12/5/68

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