IL-10 Plays a Pivotal Role in Tamoxifen-Induced Spasmolytic Polypeptide-Expressing Metaplasia in Gastric Mucosa

Background/AimsGastric cancer evolves in the pathologic mucosal milieu, and its development is characterized by both the loss of acid-secreting parietal cells and mucosal cell metaplasia, called spasmolytic polypeptide-expressing metaplasia (SPEM). Cytokines, such as interleukin (IL)-10, IL-1β, and...

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Bibliographic Details
Main Authors: Chansu Lee, Hyuk Lee, Seo Yun Hwang, Chang Mo Moon, Sung Noh Hong
Format: Article
Language:English
Published: Gastroenterology Council for Gut and Liver 2017-11-01
Series:Gut and Liver
Subjects:
Online Access:http://gutnliver.org/journal/view.html?doi=10.5009/gnl16454