ADAR Regulates RNA Editing, Transcript Stability, and Gene Expression

Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine, which is then recognized as guanosine. To study the role of ADAR proteins in RNA editing and gene regulation, we sequenced and compared the DNA and RNA of human B cells. Then, we followed up the findings experimentally with siR...

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Bibliographic Details
Main Authors: Isabel X. Wang, Elizabeth So, James L. Devlin, Yue Zhao, Ming Wu, Vivian G. Cheung
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713005718