HMGA2 Supports Cancer Hallmarks in Triple-Negative Breast Cancer

HMGA2 Supports Cancer Hallmarks in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that exhibits a high proliferation rate and early metastasis leading to a poor prognosis. HMGA2 is a DNA binding transcriptional regulator implicated in tumorigenesis. Here, we demonstrate that the <i>HMGA2</i>...

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Bibliographic Details
Main Authors: Behzad Mansoori, Mikkel Green Terp, Ali Mohammadi, Christina Bøg Pedersen, Henrik Jørn Ditzel, Behzad Baradaran, Morten Frier Gjerstorff
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
HMGA2
triple-negative breast cancer
NF-kB
IL-6
IL-8
STAT3
Online Access:https://www.mdpi.com/2072-6694/13/20/5197

Internet

https://www.mdpi.com/2072-6694/13/20/5197

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