The Potential of 2-Substituted Quinolines as Antileishmanial Drug Candidates

The Potential of 2-Substituted Quinolines as Antileishmanial Drug Candidates

There is a need for new, cost-effective drugs to treat leishmaniasis. A strategy based on traditional medicine practiced in Bolivia led to the discovery of the 2-substituted quinoline series as a source of molecules with antileishmanial activity and low toxicity. This review documents the developmen...

Full description

Bibliographic Details
Main Authors: Philippe M. Loiseau, Kaluvu Balaraman, Gillian Barratt, Sébastien Pomel, Rémy Durand, Frédéric Frézard, Bruno Figadère
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
antiparasitic drugs
2-substituted quinolines
leishmaniasis
antileishmanial agents
mechanism of action
drug targeting
Online Access:https://www.mdpi.com/1420-3049/27/7/2313

Internet

https://www.mdpi.com/1420-3049/27/7/2313

Similar Items