Phospholamban p.Leu39* Cardiomyopathy Compared with Other Sarcomeric Cardiomyopathies: Age-Matched Patient Cohorts and Literature Review

Phospholamban p.Leu39* Cardiomyopathy Compared with Other Sarcomeric Cardiomyopathies: Age-Matched Patient Cohorts and Literature Review

Hypertrophic cardiomyopathy (HCM) is a heterogeneous genetic disorder, most often caused by sarcomeric gene mutations, with a small proportion due to variants in non-sarcomeric loci. Phospholamban (PLN) is a phosphoprotein associated with the cardiac sarcoplasmic reticulum, a major determinant of ca...

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Bibliographic Details
Main Authors: Andreea Sorina Afana, Laura Vasiliu, Radu Sascău, Robert Daniel Adam, Cristina Rădulescu, Sebastian Onciul, Eliza Cinteză, Adela Chirita-Emandi, Ruxandra Jurcuț
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
phospholamban
hypertrophic cardiomyopathy
genetic testing
Online Access:https://www.mdpi.com/2308-3425/11/2/41

Internet

https://www.mdpi.com/2308-3425/11/2/41

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