<i>Drosophila</i> D-idua Reduction Mimics Mucopolysaccharidosis Type I Disease-Related Phenotypes

<i>Drosophila</i> D-idua Reduction Mimics Mucopolysaccharidosis Type I Disease-Related Phenotypes

Deficit of the IDUA (α-L-iduronidase) enzyme causes the lysosomal storage disorder mucopolysaccharidosis type I (MPS I), a rare pediatric neurometabolic disease, due to pathological variants in the <i>IDUA</i> gene and is characterized by the accumulation of the undegraded mucopolysaccha...

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Bibliographic Details
Main Authors: Concetta De Filippis, Barbara Napoli, Laura Rigon, Giulia Guarato, Reinhard Bauer, Rosella Tomanin, Genny Orso
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
lysosomal storage disorders
mucopolysaccharidosis type I
MPS I
Hurler syndrome
<i>Drosophila melanogaster</i>
fly models
Online Access:https://www.mdpi.com/2073-4409/11/1/129

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https://www.mdpi.com/2073-4409/11/1/129

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