T-cell repertoire diversity: friend or foe for protective antitumor response?
Abstract Profiling the T-Cell Receptor (TCR) repertoire is establishing as a potent approach to investigate autologous and treatment-induced antitumor immune response. Technical and computational breakthroughs, including high throughput next-generation sequencing (NGS) approaches and spatial transcr...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13046-022-02566-0 |