Strain design optimization using reinforcement learning.

Engineered microbial cells present a sustainable alternative to fossil-based synthesis of chemicals and fuels. Cellular synthesis routes are readily assembled and introduced into microbial strains using state-of-the-art synthetic biology tools. However, the optimization of the strains required to re...

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Bibliographic Details
Main Authors: Maryam Sabzevari, Sandor Szedmak, Merja Penttilä, Paula Jouhten, Juho Rousu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010177