Differentially Expressed Genes in Response to a Squalene-Supplemented Diet Are Accurate Discriminants of Porcine Non-Alcoholic Steatohepatitis

Differentially Expressed Genes in Response to a Squalene-Supplemented Diet Are Accurate Discriminants of Porcine Non-Alcoholic Steatohepatitis

Squalene is the major unsaponifiable component of virgin olive oil, the fat source of the Mediterranean diet. To evaluate its effect on the hepatic transcriptome, RNA sequencing was carried out in two groups of male Large White x Landrace pigs developing nonalcoholic steatohepatitis by feeding them...

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Bibliographic Details
Main Authors: Roubi Abuobeid, Luis V. Herrera-Marcos, Carmen Arnal, Seyed Hesamoddin Bidooki, Javier Sánchez-Marco, Roberto Lasheras, Joaquín C. Surra, María Jesús Rodríguez-Yoldi, Roberto Martínez-Beamonte, Jesús Osada
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
squalene
virgin olive oil
pigs
murine AML12 cell line
human HEPG2 cell line
transcriptome
Online Access:https://www.mdpi.com/1422-0067/24/16/12552

Internet

https://www.mdpi.com/1422-0067/24/16/12552

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