Novel Cysteine Desulfidase CdsB Involved in Releasing Cysteine Repression of Toxin Synthesis in Clostridium difficile

Clostridium difficile, a major cause of nosocomial diarrhea and pseudomembranous colitis, still poses serious health-care challenges. The expression of its two main virulence factors, TcdA and TcdB, is reportedly repressed by cysteine, but molecular mechanism remains unclear. The cysteine desulfidas...

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Bibliographic Details
Main Authors: Huawei Gu, Yingyin Yang, Meng Wang, Shuyi Chen, Haiying Wang, Shan Li, Yi Ma, Jufang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00531/full