Novel Cysteine Desulfidase CdsB Involved in Releasing Cysteine Repression of Toxin Synthesis in Clostridium difficile

Novel Cysteine Desulfidase CdsB Involved in Releasing Cysteine Repression of Toxin Synthesis in Clostridium difficile

Clostridium difficile, a major cause of nosocomial diarrhea and pseudomembranous colitis, still poses serious health-care challenges. The expression of its two main virulence factors, TcdA and TcdB, is reportedly repressed by cysteine, but molecular mechanism remains unclear. The cysteine desulfidas...

Full description

Bibliographic Details
Main Authors: Huawei Gu, Yingyin Yang, Meng Wang, Shuyi Chen, Haiying Wang, Shan Li, Yi Ma, Jufang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
clostrdium difficile
cdsB
cysteine desulfidase
toxins synthesis
δ54
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00531/full

Similar Items

Similar Items