Circlehunter: a tool to identify extrachromosomal circular DNA from ATAC-Seq data

Abstract In cancer, extrachromosomal circular DNA (ecDNA), or megabase-pair amplified circular DNA, plays an essential role in intercellular heterogeneity and tumor cell revolution because of its non-Mendelian inheritance. We developed circlehunter ( https://github.com/suda-huanglab/circlehunter ),...

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Bibliographic Details
Main Authors: Manqiu Yang, Shufan Zhang, Rong Jiang, Shaomu Chen, Moli Huang
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-023-00476-0