Associating brain imaging phenotypes and genetic risk factors via a hypergraph based netNMF method

Associating brain imaging phenotypes and genetic risk factors via a hypergraph based netNMF method

AbstractAlzheimer’s disease (AD) is a severe neurodegenerative disease for which there is currently no effective treatment. Mild cognitive impairment (MCI) is an early disease that may progress to AD. The effective diagnosis of AD and MCI in the early stage has important clinical significance.Method...

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Bibliographic Details
Main Authors: Junli Zhuang, Jinping Tian, Xiaoxing Xiong, Taihan Li, Zhengwei Chen, Rong Chen, Jun Chen, Xiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
non-negative matrix factorization
Alzheimer’s disease
mild cognitive impairment
hypergraph learning
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1052783/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1052783/full

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