Paraspeckle protein 1 (PSPC1) is involved in the cisplatin induced DNA damage response--role in G1/S checkpoint.

Paraspeckle protein 1 (PSPC1) was first identified as a structural protein of the subnuclear structure termed paraspeckle. However, the exact physiological functions of PSPC1 are still largely unknown. Previously, using a proteomic approach, we have shown that exposure to cisplatin can induce PSPC1...

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Bibliographic Details
Main Authors: Xiangjing Gao, Liya Kong, Xianghong Lu, Guanglin Zhang, Linfeng Chi, Ying Jiang, Yihua Wu, Chunlan Yan, Penelope Duerksen-Hughes, Xinqiang Zhu, Jun Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4018278?pdf=render