MicroRNA-145-5p modulates Krüppel-like factor 5 and inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma

MicroRNA-145-5p modulates Krüppel-like factor 5 and inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma

Abstract Background In several human cancers, Krüppel-like factor 5 (KLF5), a zinc finger transcription factor, can contribute to both tumor progression or suppression; however, the precise role of KLF5 in nasopharyngeal carcinoma (NPC) remains poorly understood. In this study, the association betwe...

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Bibliographic Details
Main Authors: Chien-Han Yuan, Wei-Chi Hsu, A.-Mei Huang, Ben-Chih Yuan, I.-Hung Chen, Chia-An Hsu, Rong-Feng Chen, Yih-Min Chu, Hui-Hui Lin, Hung-Lung Ke
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Molecular and Cell Biology
Subjects:
Nasopharyngeal carcinoma
MicroRNA-145-5p
Krüppel-like factor 5
Focal adhesion kinase
Cell migration
Cell invasion
Online Access:https://doi.org/10.1186/s12860-022-00430-9

Internet

https://doi.org/10.1186/s12860-022-00430-9

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