Comparative transcriptome analysis of SARS-CoV-2, SARS-CoV, MERS-CoV, and HCoV-229E identifying potential IFN/ISGs targets for inhibiting virus replication

Comparative transcriptome analysis of SARS-CoV-2, SARS-CoV, MERS-CoV, and HCoV-229E identifying potential IFN/ISGs targets for inhibiting virus replication

IntroductionSince its outbreak in December 2019, SARS-CoV-2 has spread rapidly across the world, posing significant threats and challenges to global public health. SARS-CoV-2, together with SARS-CoV and MERS-CoV, is a highly pathogenic coronavirus that contributes to fatal pneumonia. Understanding t...

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Bibliographic Details
Main Authors: Yuzhuang Liu, Tianyi Lu, Cuidan Li, Xiaotong Wang, Fei Chen, Liya Yue, Chunlai Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Medicine
Subjects:
SARS-CoV-2
SARS-CoV
MERS-CoV
IFN response
ISGs
pathogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1267903/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1267903/full

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