Codon Usage Optimization in the Prokaryotic Tree of Life: How Synonymous Codons Are Differentially Selected in Sequence Domains with Different Expression Levels and Degrees of Conservation

Codon Usage Optimization in the Prokaryotic Tree of Life: How Synonymous Codons Are Differentially Selected in Sequence Domains with Different Expression Levels and Degrees of Conservation

ABSTRACT Prokaryote genomes exhibit a wide range of GC contents and codon usages, both resulting from an interaction between mutational bias and natural selection. In order to investigate the basis underlying specific codon changes, we performed a comprehensive analysis of 29 different prokaryote fa...

Full description

Bibliographic Details
Main Authors: José Luis López, Mauricio Javier Lozano, María Laura Fabre, Antonio Lagares
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mBio
Subjects:
codon usage selection
mutational bias
genome evolution
core genes
singletons
translation efficiency
Online Access:https://journals.asm.org/doi/10.1128/mBio.00766-20

Internet

https://journals.asm.org/doi/10.1128/mBio.00766-20

Similar Items