Trypanosoma cruzi Infection Induces Cellular Stress Response and Senescence-Like Phenotype in Murine Fibroblasts
Trypanosoma cruzi infects and replicates within a wide variety of immune and non-immune cells. Here, we investigated early cellular responses induced in NIH-3T3 fibroblasts upon infection with trypomastigote forms of T. cruzi. We show that fibroblasts were susceptible to T. cruzi infection and start...
Main Authors: | Kamila Guimarães-Pinto, Danielle Oliveira Nascimento, Antonia Corrêa-Ferreira, Alexandre Morrot, Celio G. Freire-de-Lima, Marcela F. Lopes, George A. DosReis, Alessandra A. Filardy |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-07-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2018.01569/full |
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