Connexin hemichannel blockade is neuroprotective after asphyxia in preterm fetal sheep.

Asphyxia around the time of preterm birth is associated with neurodevelopmental disability. In this study, we tested the hypothesis that blockade of connexin hemichannels would improve recovery of brain activity and reduce cell loss after asphyxia in preterm fetal sheep. Asphyxia was induced by 25 m...

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Bibliographic Details
Main Authors: Joanne O Davidson, Paul P Drury, Colin R Green, Louise F Nicholson, Laura Bennet, Alistair J Gunn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4035262?pdf=render