Targeted dexamethasone nano-prodrug for corneal neovascularization management

Targeted dexamethasone nano-prodrug for corneal neovascularization management

Background: To overcome the drawbacks of traditional therapy for corneal neovascularization (CNV), we evaluated the efficacy of polyethylene glycol (PEG)-conjugated Ala-Pro-Arg-Pro-Gly (APRPG) peptide modified dexamethasone (Dex), a novel nano-prodrug (Dex-PEG-APRPG, DPA). Methods: Characterization...

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Bibliographic Details
Main Authors: Qichuan Yin, Haijie Han, Kexin Shi, Jiayue Zhou, Sifan Zheng, Ke Yao, Xingchao Shentu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Biomedical Journal
Subjects:
Corneal neovascularization
Dexamethasone
Nano-prodrug
Angiogenic vessel-homing peptide
Targeted drug delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S231941702300029X

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http://www.sciencedirect.com/science/article/pii/S231941702300029X

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