LXR regulate cholesterol homeostasis in the proximal mouse epididymis.

Oxysterol nuclear receptors liver x receptors (LXRalpha and LXRbeta) regulate lipid homeostasis when cells have to face high amounts of cholesterol and/or fatty acids. Male mice invalidated for both lxr (LXR-/-) are infertile by 5 months of age, and become sterile by the age of 9 months. The epididy...

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Bibliographic Details
Main Authors: Jean-Marc A Lobaccaro, RĂŠmi Cadet, AurĂŠlia Ouvrier, JoĂŤl R Drevet, Fabrice Saez
Format: Article
Language:English
Published: Via Medica 2010-01-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4275