Single Dose Caffeine Protects the Neonatal Mouse Brain against Hypoxia Ischemia.

In this randomized blinded study, we investigated caffeine 5 mg/kg treatment given directly after neonatal brain hypoxia ischemia. Brain morphology, behavior and key brain infiltrating immune populations were examined. Caffeine treatment significantly improves outcome when compared to phosphate buff...

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Bibliographic Details
Main Authors: Max Winerdal, Vijay Urmaliya, Malin E Winerdal, Bertil B Fredholm, Ola Winqvist, Ulrika Ådén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5271335?pdf=render