Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects.

Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects.

A significant current challenge in human genetics is the identification of interacting genetic loci mediating complex polygenic disorders. One of the best characterized polygenic diseases is Down syndrome (DS), which results from an extra copy of part or all of chromosome 21. A short interval near t...

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Bibliographic Details
Main Authors: Tamar R Grossman, Amir Gamliel, Robert J Wessells, Ouarda Taghli-Lamallem, Kristen Jepsen, Karen Ocorr, Julie R Korenberg, Kirk L Peterson, Michael G Rosenfeld, Rolf Bodmer, Ethan Bier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3207880?pdf=render

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http://europepmc.org/articles/PMC3207880?pdf=render

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