Prediction of polyspecificity from antibody sequence data by machine learning

Antibodies are generated with great diversity in nature resulting in a set of molecules, each optimized to bind a specific target. Taking advantage of their diversity and specificity, antibodies make up for a large part of recently developed biologic drugs. For therapeutic use antibodies need to ful...

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Bibliographic Details
Main Authors: Szabolcs Éliás, Clemens Wrzodek, Charlotte M. Deane, Alain C. Tissot, Stefan Klostermann, Francesca Ros
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Bioinformatics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2023.1286883/full