Interfacial Peptides as Affinity Modulating Agents of Protein-Protein Interactions

The identification of disease-related protein-protein interactions (PPIs) creates objective conditions for their pharmacological modulation. The contact area (interfaces) of the vast majority of PPIs has some features, such as geometrical and biochemical complementarities, “hot spots”, as well as an...

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Bibliographic Details
Main Authors: Pavel V. Ershov, Yuri V. Mezentsev, Alexis S. Ivanov
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/1/106