Remodeling Alzheimer-amyloidosis models by seeding

Remodeling Alzheimer-amyloidosis models by seeding

Abstract Alzheimer’s disease (AD) is among the most prevalent neurodegenerative diseases, with brain pathology defined by extracellular amyloid beta deposits and intracellular tau aggregates. To aid in research efforts to improve understanding of this disease, transgenic murine models have been deve...

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Bibliographic Details
Main Authors: Brittany S. Ulm, David R. Borchelt, Brenda D. Moore
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Molecular Neurodegeneration
Subjects:
Alzheimer’s disease
Seeding
Amyloid-β
Mouse models
Prion disease
Online Access:https://doi.org/10.1186/s13024-021-00429-4

Internet

https://doi.org/10.1186/s13024-021-00429-4

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