High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis

High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis

Highlights SRSF9 is a potential independent risk factor for HCC. High methylation status of cg06116271 predicted a better prognosis in HCC. SRSF9 knockdown inhibited the Wnt signaling pathway and cell cycle pathway. SRSF9 may serve as a potential therapeutic target for HCC.

Bibliographic Details
Main Authors: Guoshun Zhang, Bin Liu, Hua Shang, Guikai Wu, Diyang Wu, Liuqing Wang, Shengnan Li, Zhiyuan Wang, Suying Wang, Juxiang Yuan
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Medical Genomics
Subjects:
SRSF9
Hepatocellular carcinoma
Biomarkers
cg06116271
Prognosis
Online Access:https://doi.org/10.1186/s12920-022-01316-7

Internet

https://doi.org/10.1186/s12920-022-01316-7

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