Macrophages and osteoclasts stem from a bipotent progenitor downstream of a macrophage/osteoclast/dendritic cell progenitor

Abstract: Monocytes/macrophages (MΦs), osteoclasts (OCs), and dendritic cells (DCs) are closely related cell types of high clinical significance, but the exact steps in their lineage commitment are unclear. In studies on MΦ and DC development, OC development is generally not addressed. Furthermore,...

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Bibliographic Details
Main Authors: Yanling Xiao, Jara Palomero, Joanna Grabowska, Liqin Wang, Iris de Rink, Luuk van Helvert, Jannie Borst
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920303463