Mutations Located outside the Integrase Gene Can Confer Resistance to HIV-1 Integrase Strand Transfer Inhibitors

Mutations Located outside the Integrase Gene Can Confer Resistance to HIV-1 Integrase Strand Transfer Inhibitors

ABSTRACT Resistance to the integrase strand transfer inhibitors raltegravir and elvitegravir is often due to well-identified mutations in the integrase gene. However, the situation is less clear for patients who fail dolutegravir treatment. Furthermore, most in vitro experiments to select resistance...

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Manylion Llyfryddiaeth
Prif Awduron: Isabelle Malet, Frédéric Subra, Charlotte Charpentier, Gilles Collin, Diane Descamps, Vincent Calvez, Anne-Geneviève Marcelin, Olivier Delelis
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: American Society for Microbiology 2017-11-01
Cyfres:mBio
Pynciau:
3' PPT
dolutegravir
human immunodeficiency virus
integration
Mynediad Ar-lein:https://journals.asm.org/doi/10.1128/mBio.00922-17

Rhyngrwyd

https://journals.asm.org/doi/10.1128/mBio.00922-17

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