Phage-Display Based Discovery and Characterization of Peptide Ligands against WDR5

WD40 is a ubiquitous domain presented in at least 361 human proteins and acts as scaffold to form protein complexes. Among them, WDR5 protein is an important mediator in several protein complexes to exert its functions in histone modification and chromatin remodeling. Therefore, it was considered as...

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Bibliographic Details
Main Authors: Jiawen Cao, Tiantian Fan, Yanlian Li, Zhiyan Du, Lin Chen, Ying Wang, Xin Wang, Jingkang Shen, Xun Huang, Bing Xiong, Danyan Cao
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/5/1225