STING and cGAS gene expressions were downregulated among HIV-1-infected persons after antiretroviral therapy

STING and cGAS gene expressions were downregulated among HIV-1-infected persons after antiretroviral therapy

Abstract Background The HIV-1 epidemic is still considered a global public health problem, but great advances have been made in fighting it by antiretroviral therapy (ART). ART has a considerable impact on viral replication and host immunity. The production of type I interferon (IFN) is key to the i...

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Bibliographic Details
Main Authors: Lorena Leticia Peixoto de Lima, Allysson Quintino Tenório de Oliveira, Tuane Carolina Ferreira Moura, Ednelza da Silva Graça Amoras, Sandra Souza Lima, Andrea Nazaré Monteiro Rangel da Silva, Maria Alice Freitas Queiroz, Izaura Maria Vieira Cayres-Vallinoto, Ricardo Ishak, Antonio Carlos Rosário Vallinoto
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Virology Journal
Subjects:
STING
CGAS
IFN-α
Expression
HIV-1
ART
Online Access:https://doi.org/10.1186/s12985-021-01548-6

Internet

https://doi.org/10.1186/s12985-021-01548-6

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