Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome

Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome

Abstract Background Exfoliation syndrome (XFS) is an age-related systemic disorder characterized by excessive production and progressive accumulation of abnormal extracellular material, with pathognomonic ocular manifestations. It is the most common cause of secondary glaucoma, resulting in widespre...

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Bibliographic Details
Main Authors: Jibril B. Hirbo, Francesca Pasutto, Eric R. Gamazon, Patrick Evans, Priyanka Pawar, Daniel Berner, Julia Sealock, Ran Tao, Peter S. Straub, Anuar I. Konkashbaev, Max A. Breyer, Ursula Schlötzer-Schrehardt, André Reis, Milam A. Brantley, Chiea C. Khor, Karen M. Joos, Nancy J. Cox
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Genomics
Subjects:
Exfoliation syndrome
GWAS
TWAS
transcriptomics
GTEx
predicted expressions
Online Access:https://doi.org/10.1186/s12864-023-09179-7

Internet

https://doi.org/10.1186/s12864-023-09179-7

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