Studying the Effect of MBNL1 and MBNL2 Loss in Skeletal Muscle Regeneration

Studying the Effect of MBNL1 and MBNL2 Loss in Skeletal Muscle Regeneration

Loss of function of members of the muscleblind-like (MBNL) family of RNA binding proteins has been shown to play a key role in the spliceopathy of RNA toxicity in myotonic dystrophy type 1 (DM1), the most common muscular dystrophy affecting adults and children. MBNL1 and MBNL2 are the most abundantl...

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Bibliographic Details
Main Authors: Ramesh S. Yadava, Mahua Mandal, Mani S. Mahadevan
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
muscle regeneration
myotonic dystrophy
RNA toxicity
satellite cells
muscleblind
RNA binding proteins
Online Access:https://www.mdpi.com/1422-0067/25/5/2687

Internet

https://www.mdpi.com/1422-0067/25/5/2687

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