Decreased interleukin‐17RA expression is associated with good prognosis in patients with colorectal cancer and inhibits tumor growth and vascularity in mice

Abstract Background Interleukin‐17 (IL‐17) is a pro‐inflammatory cytokine that plays a vital role in the promotion of tumorigenesis in various cancers, including colorectal cancer (CRC). Based on current evidence, IL‐17 binds to interleukin‐17 receptor A (IL‐17RA); however, the role of IL‐17RA has n...

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Bibliographic Details
Main Authors: Jeng‐Kai Jiang, Chi‐Hung Lin, Ting‐An Chang, Liang‐Chuan Lo, Chien‐Ping Lin, Ruey‐Hwa Lu, Chih‐Yung Yang
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.7059