Impact of Anti PD-1 Immunotherapy on HIV Reservoir and Anti-Viral Immune Responses in People Living with HIV and Cancer

Impact of Anti PD-1 Immunotherapy on HIV Reservoir and Anti-Viral Immune Responses in People Living with HIV and Cancer

The role of immune checkpoints (ICPs) in both anti-HIV T cell exhaustion and HIV reservoir persistence, has suggested that an HIV cure therapeutic strategy could involve ICP blockade. We studied the impact of anti-PD-1 therapy on HIV reservoirs and anti-viral immune responses in people living with H...

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Bibliographic Details
Main Authors: Marine Baron, Cathia Soulié, Armelle Lavolé, Lambert Assoumou, Baptiste Abbar, Baptiste Fouquet, Alice Rousseau, Marianne Veyri, Assia Samri, Alain Makinson, Sylvain Choquet, Julien Mazières, Solenn Brosseau, Brigitte Autran, Dominique Costagliola, Christine Katlama, Jacques Cadranel, Anne-Geneviève Marcelin, Olivier Lambotte, Jean-Philippe Spano, Amélie Guihot, The French Cooperative Thoracic Intergroup (IFCT) CHIVA-2 Investigators, The ANRS Co 24 OncoVIHAC Study Group
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
immune checkpoint blockade
HIV reservoir
anti-HIV immune responses
compensatory mechanisms
Online Access:https://www.mdpi.com/2073-4409/11/6/1015

Internet

https://www.mdpi.com/2073-4409/11/6/1015

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