NADPH Alters DUOX1 Calcium Responsiveness

Hydrogen peroxide is a key element in redox signaling and in setting cellular redox tone. DUOX1 and DUOX2, that directly synthesize hydrogen peroxide, are the most abundant NADPH oxidase transcripts in most epithelia. DUOX1 and DUOX2 hydrogen peroxide synthesis is regulated by intracellular calcium...

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Bibliographic Details
Main Author: Gregory E. Conner
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724002295