Proteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome

Proteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome

IntroductionNeutrophils play a dichotomous role in community-acquired pneumonia (CAP), providing protection and potentially causing damage. Existing research on neutrophil function in CAP relies on animal studies, leaving a gap in patient-centered investigations.MethodsWe used mass spectrometry to c...

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Bibliographic Details
Main Authors: Erik H. A. Michels, Osoul Chouchane, Justin de Brabander, Alex F. de Vos, Daniël R. Faber, Renée A. Douma, Eva R. Smit, W. Joost Wiersinga, Maartje van den Biggelaar, Tom van der Poll, Arie J. Hoogendijk
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Immunology
Subjects:
community-acquired pneumonia
general ward
pneumonia
proteomics
mass spectrometry
neutrophil
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1470383/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1470383/full

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