Augmented Osteolysis in SPARC-Deficient Mice with Bone-Residing Prostate Cancer

Augmented Osteolysis in SPARC-Deficient Mice with Bone-Residing Prostate Cancer

Prostate cancer preferentially metastasizes to bone, which is rich in structural and matricellular proteins capable of altering prostate cancer progression. This study explores the role of the bone stromal matricellular protein SPARC (osteonectin/BM-40) in the progression of bone metastatic prostate...

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Bibliographic Details
Main Authors: N. Patrick McCabe, Bethany A. Kerr, Maria Madajka, Amit Vasanji, Tatiana V. Byzova
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611801090

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http://www.sciencedirect.com/science/article/pii/S1476558611801090

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