Molecular detection of fluoroquinolone resistance-associated gyrA mutations in ofloxacin-resistant clinical isolates of Mycobacterium tuberculosis from Iran and Belarus

Molecular detection of fluoroquinolone resistance-associated gyrA mutations in ofloxacin-resistant clinical isolates of Mycobacterium tuberculosis from Iran and Belarus

Objective/background: Detection of mutations in the quinolone resistance-determining region (QRDR) of the gyrA gene could determine resistance to fluoroquinolone antituberculosis drugs. The aim of this study was to detect mutations in QRDRs. Methods: From 184 clinical isolates of Mycobacterium tuber...

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Bibliographic Details
Main Authors: Mohammad Arjomandzadegan, Leonid Titov, Parissa Farnia, Parviz Owlia, Reza Ranjbar, Fatemeh Sheikholeslami, Larissa Surkova
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:International Journal of Mycobacteriology
Subjects:
gyrA
Mutation
Mycobacterium tuberculosis
Ofloxacin
Resistance
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=3;spage=299;epage=305;aulast=Arjomandzadegan

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http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=3;spage=299;epage=305;aulast=Arjomandzadegan

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