MicroRNA-149 improves osteoarthritis via repression of VCAM-1 and inactivation of PI3K/AKT pathway

MicroRNA-149 improves osteoarthritis via repression of VCAM-1 and inactivation of PI3K/AKT pathway

Objective: MicroRNAs (miRNAs) are key regulators in osteoarthritis (OA). While the role of miR-149 in OA has not been fully understood yet. This study investigated the mechanism in which miR-149 inhibited vascular cell adhesion molecule 1 (VCAM-1) via depressing PI3K/AKT pathway, thereby alleviating...

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Bibliographic Details
Main Authors: Yongqin Jiang, Lei Zhang, Huiyu Tian
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Experimental Gerontology
Subjects:
Osteoarthritis
MicroRNA-149
PI3K/AKT pathway
Vascular cell adhesion molecule-1
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556523000244

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http://www.sciencedirect.com/science/article/pii/S0531556523000244

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