PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease

PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease

BackgroundGlycolysis dysfunction is an important pathogenesis of podocyte injury in diabetic kidney disease (DKD). Foot process fusion of podocytes and increased albuminuria are markers of early DKD. Moreover, cytoskeletal remodeling has been found to be involved in the foot process fusion of podocy...

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Bibliographic Details
Main Authors: Zongwei Zhang, Wei Liang, Qiang Luo, Hongtu Hu, Keju Yang, Jijia Hu, Zhaowei Chen, Jili Zhu, Jun Feng, Zijing Zhu, Qingjia Chi, Guohua Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Endocrinology
Subjects:
PFKP
diabetic kidney diseases
glycolysis
podocyte injury
cytoskeletal remodeling
FBP
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.797025/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.797025/full

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