Melatonin promotes bone marrow mesenchymal stem cell osteogenic differentiation and prevents osteoporosis development through modulating circ_0003865 that sponges miR-3653-3p

Melatonin promotes bone marrow mesenchymal stem cell osteogenic differentiation and prevents osteoporosis development through modulating circ_0003865 that sponges miR-3653-3p

Abstract Background Little is known about the implications of circRNAs in the effects of melatonin (MEL) on bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation and osteoporosis (OP) progression. The aim of our study was to investigate circRNAs in MEL-regulated BMSC differentiation an...

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Bibliographic Details
Main Authors: Xudong Wang, Taiqiu Chen, Zhihuai Deng, Wenjie Gao, Tongzhou Liang, Xianjian Qiu, Bo Gao, Zizhao Wu, Jincheng Qiu, Yuanxin Zhu, Yanbo Chen, Zhancheng Liang, Hang Zhou, Caixia Xu, Anjing Liang, Peiqiang Su, Yan Peng, Dongsheng Huang
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Stem Cell Research & Therapy
Subjects:
Melatonin
Osteogenic differentiation
BMSCs
Osteoporosis
circ_0003865
miR-3653-3p
Online Access:https://doi.org/10.1186/s13287-021-02224-w

Internet

https://doi.org/10.1186/s13287-021-02224-w

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