Molecular characterization of the circadian clock in paediatric leukaemia patients: a prospective study protocol

Abstract Background In many organisms, including humans, the timing of cellular processes is regulated by the circadian clock. At the molecular level the core-clock consists of transcriptional-translational-feedback loops including several genes such as BMAL1, CLOCK, PERs and CRYs generating circa 2...

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Bibliographic Details
Main Authors: Marius Ludwig, Alireza Basti, Müge Yalçin, Johannes H. Schulte, Angela Relógio
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Pediatrics
Subjects:
Online Access:https://doi.org/10.1186/s12887-023-03921-6