The Effect of S-15176 Difumarate Salt on Ultrastructure and Functions of Liver Mitochondria of C57BL/6 Mice with Streptozotocin/High-Fat Diet-Induced Type 2 Diabetes

S-15176, a potent derivative of the anti-ischemic agent trimetazidine, was reported to have multiple effects on the metabolism of mitochondria. In the present work, the effect of S-15176 (1.5 mg/kg/day i.p.) on the ultrastructure and functions of liver mitochondria of C57BL/6 mice with type 2 diabet...

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Bibliographic Details
Main Authors: Natalia V. Belosludtseva, Vlada S. Starinets, Lyubov L. Pavlik, Irina B. Mikheeva, Mikhail V. Dubinin, Konstantin N. Belosludtsev
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/10/309