Labeling of carcinoembryonic antigen-specific CAR-T cells with superparamagnetic iron oxide nanoparticles and in vitro magnetic resonance imaging

Objective To use superparamagnetic iron oxide nanoparticles (SPIONs) to label chimeric antigen receptor (CAR) T cells targeting carcinoembryonic antigen (CEA), and perform magnetic resonance imaging (MRI) to real time trace CEA CAR-T cells in vivo. Methods Appropriate amount of ferumoxytol, heparin...

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Bibliographic Details
Main Authors: HE Kungao, JIANG Bo, GUO Mudan
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2024-09-01
Series:陆军军医大学学报
Subjects:
Online Access:https://aammt.tmmu.edu.cn/html/202404042.htm